MAC-545496-抑制剂-深圳欣博盛生物科技有限公司

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MAC-545496

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-0163-M001	规格：1 mg	目录价：￥360
货号：AG-CR1-0163-M005	规格：5 mg	目录价：￥600
货号：AG-CR1-0163-M025	规格：25 mg	目录价：￥1680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MAC-545496

别名:

N-((5-Chloropyridin-2-yl)carbamothioyl)-3-nitro-4-(piperidin-1-yl)benzamide

产品描述:

MAC-545496 is a potent antimicrobial agent against MRSA. It works as a synthetic antibiotic adjuvant, a antivirulence and antibiofilm agent. Potent nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR), a regulator of the cell-envelope stress response that is an important virulence factor and determinant of antibiotic resistance. Antivirulence compound that reverses beta-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA) strains. MAC-545496 cripples MRSA’s ability to cause infection by diminishing its tolerance to the hostile components of the immune system and blocking the bacterium’s capacity to resist the action of several front-line antibiotics. Inhibits biofilm formation and abrogates intracellular survival in macrophages. MAC-545496 targets the bacteria in several different ways, it makes MRSA more susceptible to attack from the immune system, renders it vulnerable to the action of several antibiotics again and reduces the bacteria’s ability to produce biofilms.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

419.9

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)