货号:SBB-DE0025-C050 | 规格:50 ug | 目录价:¥2814 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NEDP1 [SENP8] (human) (rec.) (His)
别名:
NEDD8-specific Protease 1; Sentrin-specific Protease 8; Deneddylase-1; Sentrin/SUMO-specific Protease SENP8; DEN1; PRSC2
产品描述:
NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which hydrolyzes the isopeptide bond between the C-terminus of NEDD8 and the respective lysine of the substrate protein to which the NEDD8 is covalently bound. NEDP1 is important in regulating cullin associated ubiquitin ligase enzymes such as those of the SCF (Skp-Cullin-Fbox) family and subsequently, it is important in regulating cell cycle progression and other biological functions.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~27kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5, 100mM sodium chloride, 1mM TCEP.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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