官网链接
折扣/货期| 货号：FY12017 | 规格：100 ul | 目录价：￥6488 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NELFB Antibody / Negative elongation factor B / COBRA1
产品描述:
NELFB antibody targets negative elongation factor B, also known as COBRA1, a transcriptional regulator involved in RNA polymerase II pausing. NELFB functions as part of the NELF complex, which includes NELFA, NELFC/D, and NELFE subunits. This complex stabilizes paused RNA polymerase II at promoter-proximal regions, ensuring proper regulation of transcriptional elongation. By fine-tuning transcription, NELFB contributes to developmental programs and cellular stress responses.
Studies with NELFB antibody have implicated the protein in cancer biology and hormone signaling. COBRA1 was first identified as a BRCA1-associated factor, and disruption of NELFB function has been linked to breast cancer progression and altered estrogen receptor activity. Beyond cancer, NELFB also regulates genes involved in embryonic development and immune responses, making it a versatile factor for gene expression studies.
Validated antibody clones for NELFB detection work in assays such as western blot, chromatin immunoprecipitation, and immunohistochemistry. These reagents enable researchers to study promoter-proximal pausing, transcriptional control, and protein-protein interactions within the NELF complex. Clone validation ensures specificity for NELFB rather than closely related transcriptional regulators.
NSJ Bioreagents supplies this NELFB antibody for studies in transcription regulation, cancer pathways, and developmental biology. Alternate names include negative elongation factor B antibody, COBRA1 antibody, and cofactor of BRCA1 antibody.
Studies with NELFB antibody have implicated the protein in cancer biology and hormone signaling. COBRA1 was first identified as a BRCA1-associated factor, and disruption of NELFB function has been linked to breast cancer progression and altered estrogen receptor activity. Beyond cancer, NELFB also regulates genes involved in embryonic development and immune responses, making it a versatile factor for gene expression studies.
Validated antibody clones for NELFB detection work in assays such as western blot, chromatin immunoprecipitation, and immunohistochemistry. These reagents enable researchers to study promoter-proximal pausing, transcriptional control, and protein-protein interactions within the NELF complex. Clone validation ensures specificity for NELFB rather than closely related transcriptional regulators.
NSJ Bioreagents supplies this NELFB antibody for studies in transcription regulation, cancer pathways, and developmental biology. Alternate names include negative elongation factor B antibody, COBRA1 antibody, and cofactor of BRCA1 antibody.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, IHC, ICC, IF
同种型:
Rabbit IgG
免疫原:
A synthesized peptide derived from human NELFB was used as the immunogen for the NELFB antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
32C80
纯化方式:
Affinity-chromatography
保存温度:
Store the NELFB antibody at -20oC.
产品形式:
Liquid
存储溶液:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
产地:
美国
促销活动
相关产品推荐
Recombinant Desmin Antibody
货号：V9768-100UG
Recombinant Desmin Antibody
货号：V9768SAF-100UG
Recombinant Prostein Antibody / SLC45A3
货号：V9764-100UG
Recombinant Prostein Antibody / SLC45A3
货号：V9764SAF-100UG
Recombinant POU2F2 Antibody / OCT2
货号：V9765-100UG
Recombinant POU2F2 Antibody / OCT2
货号：V9765SAF-100UG
复制QQ号成功，请打开QQ后添加好友进行咨询