官网链接
折扣/货期| 货号：44975-10 mg | 规格：10 mg | 目录价：￥1621 |
| 货号：44975-25 mg | 规格：25 mg | 目录价：￥3363 |
| 货号：44975-5 mg | 规格：5 mg | 目录价：￥898 |
| 货号：44975-50 mg | 规格：50 mg | 目录价：￥6285 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Nerandomilast
别名:
BI-1015550
产品描述:
A PDE4B inhibitor (IC50 = 0.01 µM); selective for PDE4B over PDE4A, PDE4C, and PDE4D (IC50s = 0.248, 8.7, and 0.091 µM, respectively), PDE7A, PDE3A, PDE1C, and PDE9A (IC50s = 14, 120, 46, and >100 µM, respectively), and does not inhibit PDE2A, PDE5, or PDE6; inhibits LPS-induced TNF-α release and phytohemagglutinin P-induced IL-2 release in isolated human PBMCs (IC50s = 0.035 and 0.009 µM, respectively); exhibits a lower emetic potential than roflumilast in Asian house shrews; reduces bleomycin-induced decreases in forced vital capacity and static lung volume in a mouse model of pulmonary fibrosis at 12.5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
448.97
产品形式:
A solid
纯度:
≥98%
CAS号:
1423719-30-5
分子式:
C20H25ClN6O2S
促销活动
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