Netrin-1 (human):Fc (human) (rec.)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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Netrin-1 (human):Fc (human) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40B-0075-3010	规格：3 x 10 ug	目录价：￥6960
货号：AG-40B-0075-C010	规格：10 ug	目录价：￥3480
货号：AG-40B-0075-C100	规格：100 ug	目录价：￥15600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Netrin-1 (human):Fc (human) (rec.)

别名:

NTN1

产品描述:

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.

宿主来源:

HEK 293 cells

靶标/特异性:

Binds to human, mouse and rat UNC5B.

产品浓度:

0.1mg/ml after reconstitution

保存温度:

+4°C

运输温度:

预期分子量:

~90kDa (SDS-PAGE)

产品形式:

solid

存储溶液:

Lyophilized. Contains PBS plus protein stabilizer. No BSA included. The protein stabilizer shows no interference with protein activity.

产地:

瑞士

纯度:

>95% (SDS-PAGE)

生物活性:

Induces pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by inhibiting apoptosis mediated by the receptors DCC or UNC5B (at 150ng /ml). Induces axon outgrowth.

内毒素水平:

<0.1EU/µg purified protein (LAL test; Lonza).

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