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折扣/货期| 货号：GTX54845 | 规格：50μl | 目录价：￥10400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Neurexin 1 antibody
别名:
neurexin 1 , Nrxn1b
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-Fr, LCI, WB
同种型:
IgG
免疫原:
Peptide (C)KPRHQKDAKHPQMIK, corresponding to amino acid residues 546-560 (Extracellular, N-terminus) of rat Neurexin 1α (Accession : Q63372).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
168
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. [provided by RefSeq, Nov 2016]
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