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折扣/货期| 货号：GTX41327 | 规格：200μg | 目录价：￥6500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Neutrophil elastase antibody [39A]
别名:
elastase, neutrophil expressed , ELA2 , GE , HLE , HNE , NE , PMN-E , SCN1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, Functional Assay
靶标/特异性:
This antibody is specific for human neutrophil elastase.
同种型:
IgG1
免疫原:
Elastase from human neutrophils
克隆性:
Monoclonal
克隆号:
39A
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016]
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