| 货号:SIH-406-1G | 规格:1 g | 目录价:¥648 |
产品详情
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产品名称:
Niclosamide
别名:
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
产品描述:
Autophagy inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
327.12
产品形式:
Pale yellow solid
产地:
加拿大
功能与背景:
Niclosamide is part of the anthelmintics drug class, which are used to treat tapeworm infections in humans. Niclosamide has been shown to selectively inhibit the Stat-3 signalling pathway, specifically by inhibiting its activation, nuclear translocation and transcriptional activity. It has also been reported that Niclosamide inhibits mTORC1, thereby inducing autophagy and increasing the formation of autophagosomes.
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
50-65-7
分子式:
C13H8Cl2N2O4
溶解度:
Soluble to 25 mM in ethanol and to 10 mM in DMSO
PubChem CID:
4477
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