NKX2.1 Antibody / TFF-1 / Thyroid transcription factor 1-单抗-深圳欣博盛生物科技有限公司

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NKX2.1 Antibody / TFF-1 / Thyroid transcription factor 1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5801SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

NKX2.1 Antibody / TFF-1 / Thyroid transcription factor 1

产品描述:

Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1) and Homeobox protein Nkx-2.1. NKX2.1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of NKX2.1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. NKX2.1 reactivity is also seen in thyroid malignancies.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2a, kappa

免疫原:

A portion of amino acids 1-200 from human TTF-1 protein was used as the immunogen for the NKX2.1 antibody.

克隆性:

Monoclonal (mouse origin)