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折扣/货期| 货号：AG-40A-0153T-3010 | 规格：3 x 10 ug | 目录价：￥3360 |
| 货号：AG-40A-0153T-C010 | 规格：10 ug | 目录价：￥1680 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NMNAT2 (human) (rec.) (His)
别名:
Nicotinamide Mononucleotide Adenylyltransferase 2; NMN Adenylyltransferase 2; NaMN Adenylyltransferase 2
产品描述:
Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~35kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl plus 0.025% CHAPS.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
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