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折扣/货期| 货号：GTX70897 | 规格：25μg | 目录价：￥3800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NR0B2 antibody
别名:
nuclear receptor subfamily 0 group B member 2 , NR0B2 , SHP , SHP1
反应种属:
Hamster, Human, Monkey, Mouse, Rabbit
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P
同种型:
IgG
免疫原:
Synthetic 16 amino acid peptide from ligand-binding domain of human NR0B2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]
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