| 货号:23499-1 mg | 规格:1 mg | 目录价:¥549.4 |
| 货号:23499-10 mg | 规格:10 mg | 目录价:¥2626.4 |
| 货号:23499-25 mg | 规格:25 mg | 目录价:¥5855.8 |
| 货号:23499-5 mg | 规格:5 mg | 目录价:¥1715.2 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NSC 668036
产品描述:
An inhibitor of the Dvl PDZ domain (Kd = 240 μM for mouse Dvl1 PDZ domain); reduces expression of the Wnt target gene, Siamois, in Xenopus embryos and inhibits the ability of injected Wnt3A to induce formation of a secondary axis (180 ng); inhibits proliferation of NIH/3T3 fibroblasts, restrains their migration in a scratch assay, and blocks the accelerating effect of TGF-β on fibroblast migration (>10 μM); reduces the severity of bleomycin-induced pulmonary fibrosis and expression of α-SMA collagen I, TGF-β, and β-catenin in lung in mice (5 mg/kg per day for 14 days)
保存温度:
-20
运输温度:
-20
预期分子量:
460.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
144678-63-7
分子式:
C21H36N2O9
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