NUP98 antibody [21A10]-单抗-深圳欣博盛生物科技有限公司

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NUP98 antibody [21A10]

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX00695

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

NUP98 antibody [21A10]

别名:

nucleoporin 98 , ADIR2 , NUP196 , NUP96

反应种属:

Human, Mouse, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena

宿主来源:

Mouse

实验应用:

ICC/IF, WB

靶标/特异性:

For WB application, it works on S. cerevisiae and S. pombe nut may be not suitbale for human, T. etrahymena and yeasts. Recommend GTX00693 NUP98 antibody [13C2] on human, T. etrahymena and yeasts samples.

同种型:

IgG1

免疫原:

Synthetic peptides containing conserved N-terminal sequence, GLFG, of Nup98 protein of Tetrahymena thermophila.
Peptide 1; 1-MFGNTGGGGLFGNTQTQQTGGGLFGQPQQ-29
Peptide 2; 646-SNPTQGGGLFGAANPGLGG-664
Epitope determined: GLF

克隆性:

Monoclonal

克隆号:

21A10

纯化方式:

Purified IgG

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

198

产品形式:

Liquid

存储溶液:

Filter-sterilized PBS, 50% Glycerol, no preservatives.

生产商:

GeneTex

功能与背景:

Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin. [provided by RefSeq, Feb 2016]

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