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折扣/货期| 货号：AG-CR1-3593-C250 | 规格：250 ug | 目录价：￥1560 |
| 货号：AG-CR1-3593-M001 | 规格：1 mg | 目录价：￥3240 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
OCH
别名:
(2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-tetracosanoyl-2-amino-1,3,4-nonanetriol)
产品描述:
Truncated analog of alpha-GalCer. iNKT cell glycolipid agonist. Immunosuppressive. Th2 polarizing. Stimulation of NKT with OCH results in release of primarily Th2 cytokine compared to stimulation with alpha-GalCer, which results in release of a mixture of Th1 and Th2 cytokines. Induces stronger interleukin-4 (IL-4) secretion and weaker interferon-gamma (IFN-gamma) secretion than alpha-GalCer both in vitro and in vivo. Inducer of interleukin-10 (IL-10) and suppressor of diabetes. Shown to prevent experimental autoimmune encephalomyelitis (EAE) in mice, an animal model of multiple sclerosis. Has beneficial effects on type I diabetes in NOD mice. Suppressor of collagen-induced arthritis. Might be useful for immunotherapy of transplant rejection.
保存温度:
+4°C
运输温度:
BI
预期分子量:
704
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
383187-82-4
分子式:
C39H77NO9
溶解度:
Soluble in DMSO, 100% ethanol (warm) or methanol (warm).
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