深圳欣博盛生物科技有限公司 a1

Orai1 antibody
货号:GTX85048 规格:100μg 目录价:¥6200
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Orai1 antibody
别名:
ORAI calcium release-activated calcium modulator 1 , CRACM1 , IMD9 , ORAT1 , TAM2 , TMEM142A
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ELISA, IHC-P, WB
靶标/特异性:
This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
同种型:
IgG
免疫原:
ORAI1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1.The immunogen is located within the last 50 amino acids of ORAI1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
33
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one form of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
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