| 货号:SIH-624-5MG | 规格:5 mg | 目录价:¥2577.6 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Oridonin
别名:
7a,20-Epoxy-1a,6b,7,14-tetrahydroxykaur-16-en-15-one; Isodonol
产品描述:
HSP70 inhibitor & NLRP inflammasome inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
364.4
产品形式:
White to off-white powder
产地:
加拿大
功能与背景:
A potent, covalent inhibitor of the NLRP3 inflammasome with anti-inflammatory activity in various mouse models (1). Inhibits vascular inflammation in vivo (2). Inhibits aberrant AKT activation in human breast cancer cells with hyperactivated PI3K/AKT signaling (3). Inhibits migration, invasion and adhesion of melanoma cells (4). Induces apoptosis in osteosarcoma cells by multiple pathways (5).
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
28957-04-2
分子式:
C20H28O6
溶解度:
May be dissolved in DMSO (50 mg/ml); or Ethanol (10 mg/ml, warm)
PubChem CID:
5321010
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