OTX2 Antibody / Orthodenticle homolog 2-单抗-深圳欣博盛生物科技有限公司

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OTX2 Antibody / Orthodenticle homolog 2

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5537SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

OTX2 Antibody / Orthodenticle homolog 2

产品描述:

Transcription factors OTX1 and OTX2, two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q22.3, respectively.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, FACS

同种型:

Mouse IgG1,

免疫原:

Recombinant human full-length OTX2 protein was used as the immunogen for the OTX2 antibody.

克隆性:

Monoclonal (mouse origin)