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折扣/货期| 货号：GTX22452 | 规格：500μl | 目录价：￥2300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p107 peptide
别名:
RB transcriptional corepressor like 1 , CP107 , PRB1 , p107
实验应用:
IP
克隆号:
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store this product at 4ºC, DO NOT FREEZE. The product is stable for one year from the date of shipment.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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