p21 peptide-其他肽-深圳欣博盛生物科技有限公司

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p21 peptide

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX28015

规格：100μg

目录价：￥2300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

p21 peptide

别名:

cyclin dependent kinase inhibitor 1A , CAP20 , CDKN1 , CIP1 , MDA-6 , P21 , SDI1 , WAF1 , p21CIP1

实验应用:

克隆号:

偶联:

Unconjugated

产品浓度:

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Keep as concentrated solution, aliquot and store at 4ºC.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, BSA, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Sep 2015]

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