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折扣/货期| 货号：39845-1 mg | 规格：1 mg | 目录价：￥1313 |
| 货号：39845-10 mg | 规格：10 mg | 目录价：￥7223 |
| 货号：39845-5 mg | 规格：5 mg | 目录价：￥3940 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
P276-00 (hydrochloride)
别名:
Riviciclib
产品描述:
A Cdk9, Cdk4, and Cdk1 inhibitor (IC50s = 0.020, 0.063, and 0.079 µM, respectively); selective for these CDKs over Cdk2/cyclin E, Cdk2/cyclin A, Cdk6, and Cdk7 (IC50s = 2.54, 0.224, 0.396, and 2.87 µM, respectively), as well as a panel of eight other kinases; induces apoptosis in HL-60 cells at 1 µM; induces cell cycle arrest at the G1 phase in synchronized H460 cells at 1.5 and 5 µM; reduces tumor volume in a H460 mouse xenograft model at 50 mg/kg once per day; inhibits reactivation of latent HIV-1 induced by prostratin, panobinostat, or JQ-1 in 24ST1NLESG cells (IC50s = 0.1, 0.07, and 0.075 µM, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
401.83994
产品形式:
A solid
纯度:
≥98%
CAS号:
920113-03-7
分子式:
C21H20ClNO5 • HCl
促销活动
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