PXS-5505 (hydrochloride)-抑制剂-深圳欣博盛生物科技有限公司

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PXS-5505 (hydrochloride)

品牌：Cayman

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说明书

折扣/货期

货号：39857-10 mg	规格：10 mg	目录价：￥2894
货号：39857-25 mg	规格：25 mg	目录价：￥6365
货号：39857-5 mg	规格：5 mg	目录价：￥1702
货号：39857-50 mg	规格：50 mg	目录价：￥10171

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PXS-5505 (hydrochloride)

产品描述:

A pan inhibitor of LOX and LOXL1-4 (IC50s = 0.493, 0.159, 0.57, 0.18, and 0.19 µM for fibroblast LOX and recombinant human LOXL1-4, respectively); selective for LOX and LOXL1-4 over DAO, VAP-1, MAO-A, and MAO-B (IC50s = >30 µM for all); reduces bleomycin-induced increases in dermal thickness and the levels of α-smooth muscle actin in a mouse model of systemic sclerosis at 15 mg/kg; reduces collagen crosslinking in KPC CAF 3D organotypic matrices; increases survival to a greater extent than gemcitabine alone when administered in combination with gemcitabine, reduces gemcitabine-induced increases in collagen levels and stiffness, and reduces liver metastatic burden in autochthonous KPC pancreatic ductal adenocarcinoma mouse models at 20 mg/kg

保存温度:

-20

运输温度:

-20

预期分子量:

280.319003

产品形式:

A solid

纯度:

≥98%

CAS号:

2409964-23-2