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折扣/货期| 货号：13-261 | 规格：100 uL | 目录价：￥7423.65 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
P4HB Antibody
别名:
Protein disulfide isomerase family A member 1, DSI, GIT, PDI, PHDB, PO4DB, PO4HB, PROHB, ERBA2L, P4Hbeta
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB,IHC,Flow
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
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