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折扣/货期| 货号：GTX28590 | 规格：500μl | 目录价：￥4700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p53 antibody [B20.1 (BP 53.122)]
别名:
tumor protein p53 , BCC7 , BMFS5 , LFS1 , P53 , TRP53
反应种属:
Hamster, Human, Monkey, Mouse, Rat
宿主来源:
Mouse
实验应用:
IHC-P, WB
靶标/特异性:
This antibody reacts with wild type as well as mutant type of the p53 protein. It recognizes an epitope in the N-terminus of the human p53 protein. This antibody recognizes cell nuclei in which the p53 protein are generally localized. This antibody does not react with normal fibroblasts.
同种型:
IgG2a
免疫原:
Recombinant full length protein (Human).
克隆性:
Monoclonal
克隆号:
B20.1 (BP 53.122)
纯化方式:
IgG fraction
偶联:
Unconjugated
产品浓度:
0.35 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
44
产品形式:
Liquid
存储溶液:
PBS, 0.2% BSA, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
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