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折扣/货期| 货号：GTX11997 | 规格：50μg | 目录价：￥4700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
p73 delta N antibody [38C674.2]
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-Fr, IHC-P, WB
同种型:
IgG1
免疫原:
This antibody was developed against a peptide corresponding to a portion of amino acid residues 1-50 of human dNp73. Mouse and human sequences are more than 95 % identical at these amino acid residues. In mouse, alanine at position 8 is replaced by methionine.
克隆性:
Monoclonal
克隆号:
38C674.2
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Even though the tumor suppressor gene p53 is highly important in human cancer, as indicated by the fact that it is mutated in about 50% of cases, up to a few years ago no similar proteins had been identified. Two p53 homologues are now identified, p73 and p63, with high amino acid identity suggesting similar functions. Both p63 and p73 have two significant structural peculiarities compared with p53; the presence of an extended non-conserved C-terminus containing a sterile alpha motive (SAM), (typical of developmental proteins), and the presence of number of different splicing isoforms differing in the N-terminus or in the absence of the transactivation domain (delta N forms).
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