PAD4 Inhibitor Screening Assay Kit (AMC)-抑制剂筛选试剂盒-深圳欣博盛生物科技有限公司

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PAD4 Inhibitor Screening Assay Kit (AMC)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：701320

规格：96 wells

目录价：￥7276.2

产品详情

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产品名称:

PAD4 Inhibitor Screening Assay Kit (AMC)

别名:

PADI4|PADI5|PDI5|Peptidylarginine Deiminase 4|Protein Arginine Deiminase 4

产品描述:

Cayman’s PAD4 Inhibitor Screening Assay Kit (AMC) provides a convenient method for screening human PAD4 inhibitors. This assay utilizes a fluorescent substrate (Z-Arg-AMC) consisting of an arginine residue, a carboxybenzyl group, and a fluorophore (7-amino-4-methylcoumarin, AMC).7 Acylation of AMC onto the arginine residue masks the fluorescence of the fluorophore. In the absence of PAD4, the substrate remains unaltered, allowing the developer to release free AMC. In the presence of PAD4, the arginine of the substrate is citrullinated, and while the reaction is quenched by the addition of developer, free AMC is not released. Fluorescence is analyzed with an excitation wavelength of 355-365 nm and an emission wavelength of 445-455 nm. The fluorescent signal is inversely proportional to the amount of citrullination by PAD4.

保存温度:

-80

运输温度:

-80

有效期:

730

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