| 货号:GTX26401 | 规格:100μl | 目录价:¥6300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
pan Cytokeratin antibody [PCK-26]
产品描述:
Pan-Cytokeratin antibody [PCK-26] is a mouse monoclonal antibody that detects multiple cytokeratins (i.e., Type II cytokeratins 1, 5, 6, and 8), a group of intermediate filament proteins present in most human epithelial tissues. This reagent is a broad spectrum antibody that reacts with a variety of normal, reactive, and neoplastic epithelial tissues, as well as simple, cornifying, and non-cornifying squamous epithelia and pseudostratified epithelia.
反应种属:
Bovine, Carp, Cat, Chicken, Dog, Goat, Guinea pig, Hamster, Human, Lizard, Mouse, Pig, Rabbit, Rat, Sheep, Snake
宿主来源:
Mouse
实验应用:
Blocking, Dot, FCM, ICC/IF, IHC, IHC-Fr, IHC-P, Multiplexing, WB
靶标/特异性:
The antibody recognizes an epitope located on the Type II cytokeratins 1, 5, 6, and 8. PCK-26 is a broad spectrum antibody which reacts specifically with a variety of normal, reactive, and neoplastic epithelial tissues. The antibody reacts with simple, cornifying, and non-cornifying squamous epithelia and pseudostratified epithelia.
同种型:
IgG1
免疫原:
cytokeratin from human epidermis.
克隆性:
Monoclonal
克隆号:
PCK-26
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
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