PARP-1 [ARTD1] (E988K Mutant) (human) (rec.) Control-其他重组蛋白-深圳欣博盛生物科技有限公司

首页产品中心其他重组蛋白

PARP-1 [ARTD1] (E988K Mutant) (human) (rec.) Control

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40T-0015-C010

规格：10 ug

目录价：￥1680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PARP-1 [ARTD1] (E988K Mutant) (human) (rec.) Control

别名:

Poly(ADP-ribose) Polymerase 1; ADP-ribosyltransferase Diphtheria Toxin-like 1; NAD(+) ADP-ribosyltransferase 1

产品描述:

PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. PARP-1 (E988K mutant) is an inactive form of PARP-1 which can be used as a control compound.

宿主来源:

Sf21 cells

产品浓度:

Lot dependent (0.2-0.5mg/ml)

保存温度:

-20°C

运输温度:

产品形式:

liquid

存储溶液:

Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol.

产地: