| 货号:AG-40T-0013-C010 | 规格:10 ug | 目录价:¥3120 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PARP-3 [ARTD3] (human) (rec.) (His) (high purity)
别名:
Poly(ADP-ribose) Polymerase 3; ADP-ribosyltransferase Diphtheria Toxin-like 3; NAD(+) ADP-ribosyltransferase 3
产品描述:
PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
宿主来源:
Sf21 cells
产品浓度:
Lot dependent (0.2-1mg/ml)
保存温度:
-20°C
运输温度:
DI
产品形式:
liquid
存储溶液:
Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
>10U/mg protein (only monoADP-ribosyl transferase activity).
上一个:PARP-2 [ARTD2] (mouse) (rec.) (His) (high purity)
下一个:PARP-1 [ARTD1] (E988K Mutant) (human) (rec.) Control
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