PBX2 Antibody-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

PBX2 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9707SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PBX2 Antibody

产品描述:

Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, FACS, IF

同种型:

Mouse IgG2b

免疫原:

Recombinant full-length human PBX2 protein was used as the immunogen for the PBX2 antibody.

克隆性:

Monoclonal (mouse origin)