深圳欣博盛生物科技有限公司 a1

PD 082106
货号:29719-1 mg 规格:1 mg 目录价:¥482
货号:29719-10 mg 规格:10 mg 目录价:¥2720
货号:29719-5 mg 规格:5 mg 目录价:¥1715
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PD 082106
别名:
5’-FIO|5′-Fluoroindirubinoxime
产品描述:
An inhibitor of FLT3 kinase (IC50 = 0.015 µM); selective for FLT3 over Met, Ron, EGFR, and the insulin receptor (IC50s = >10 µM for all) but does inhibit DRAK2 (IC50 = 0.62 µM), as well as VEGFR2 and Aurora A (IC50s = 1.53 and 1.27 µM, respectively); inhibits proliferation of A549, SNU-638, HT-1080, HL-60, and MCF-7 cancer cells (IC50s = 13, 2.1, 3.4, 89, and 9 µM, respectively); inhibits proliferation of (IC50 = 5.1 µM), and induces apoptosis in, RK3E-ras cells and reduces tumor growth in RK3E-ras flank and oral tumor models; active against the parasite T. gondii (ID50 = 0.52 µM) with a TD50 value of 61 µM
保存温度:
-20
运输温度:
-20
预期分子量:
295.268023
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
861214-33-7
分子式:
C16H10FN3O2
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