深圳欣博盛生物科技有限公司 a1

PD 166285
货号:26804-1 mg 规格:1 mg 目录价:¥549.4
货号:26804-10 mg 规格:10 mg 目录价:¥3149
货号:26804-25 mg 规格:25 mg 目录价:¥7155.6
货号:26804-5 mg 规格:5 mg 目录价:¥1715.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PD 166285
产品描述:
A tyrosine kinase inhibitor; inhibits Src, FGFR1, EGFR, and PDGFRβ (IC50s = 8.4, 39.3, 87.5, and 98.3 nM, respectively), as well as WEE1 (IC50 = 24 nM); inhibits PDGF- or EGF-induced receptor autophosphorylation in VSMCs and A431 cells, respectively, and bFGF-induced tyrosine phosphorylation in Sf9 cells (IC50s = 6.5, 1,600, and 97.3 nM, respectively); inhibits chemotaxis and growth of, as well as adhesion to vitronectin by, VSMCs (IC50s = 80-120 nM); inhibits radiation-induced cell cycle arrest at the G2/M phase and enhances radiation-induced cell death in HT-29 cells; inhibits angiogenesis and induces tumor regression in a 16c murine mammary carcinoma model when administered in combination with PDT at 1, 5, and 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
512.4
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
185039-89-8
分子式:
C26H27Cl2N5O2
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