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折扣/货期| 货号：GTX04362 | 规格：500μl | 目录价：￥11100 |
| 货号：GTX04362-S | 规格：100μl | 目录价：￥4200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PD-L1 antibody [MSVA-711R] HistoMAX™
别名:
CD274 molecule , B7-H , B7H1 , PD-L1 , PDCD1L1 , PDCD1LG1 , PDL1
产品描述:
This antibody was validated on 76 different Normal Tissues by IHC-P.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
<b>Highly recommended for IHC-P in human tissues.</b>
同种型:
IgG
免疫原:
KLH-conjugated linear peptide corresponding to human PD-L1
克隆性:
Monoclonal
克隆号:
MSVA-711R
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
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