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折扣/货期| 货号：40-158-0.002 mg | 规格：0.002 mg | 目录价：￥3783 |
| 货号：40-158-0.01 mg | 规格：0.01 mg | 目录价：￥5674.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PDGF-BB Recombinant Protein
别名:
SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2, SIS, Platelet-derived growth factor subunit B, PDGF subunit B
表达系统:
E. coli
保存温度:
The lyophilized PDGF-BB recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted PDGF-BB is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing PDGF-BB recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
生物活性:
Biological activity was determined by the dose - dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 1.0 - 3.0 ng/mL.
Accession #:
NP_002599.1
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