PDGF-BB Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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PDGF-BB Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：40-607

规格：0.01 mg

目录价：￥6493.5

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PDGF-BB Recombinant Protein

别名:

SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2, SIS, Platelet-derived growth factor subunit B, PDGF subunit B

表达系统:

E. coli

保存温度:

The lyophilized PDGF-BB recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted PDGF-BB is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing PDGF-BB recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Blue Ice

产品形式:

Lyophilized

产地:

美国

生产商:

Prosci

功能与背景:

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-β. PDGFR-a is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). .

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 1.0-3.0 ng/mL.

Accession #:

NP_002599.1

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