Periostin (mouse) ELISA Kit-小鼠ELISA试剂盒-深圳欣博盛生物科技有限公司

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Periostin (mouse) ELISA Kit

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-45B-0005-KI01

规格：96 wells

目录价：￥6120

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Periostin (mouse) ELISA Kit

别名:

Osteoblast-specific Factor 2; OSF-2; Postn

产品描述:

Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin up-regulation in cancers usually correlates with aggressiveness and/or poor survival. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.

靶标/特异性:

Detects natural and recombinant mouse periostin. Has been tested on mouse periostin isoform 5 (should also detect mouse isoforms 1, 2 and 3 according to sequences). Mouse isoform 4 has not been tested.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

10pg/ml

检测范围:

31 to 2000pg/ml

检测方法:

Colorimetric

样本类型: