| 货号:AG-45A-0007YEK-KI01 | 规格:96 wells | 目录价:¥7920 |
| 货号:AG-45A-0007YTP-KI01 | 规格:2 x 96 wells | 目录价:¥13680 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit
别名:
Nicotinamide Phosphoribosyltransferase; PBEF1; Pre-B Cell Colony Enhancing Factor 1
产品描述:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohn’s disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health. Recently NAMPT extracellular (eNAMPT) has been shown to be secreted from macrophages in muscles and to triggers a proliferative signal of muscle stem cell (MusC) by binding to CCR5 located at the surface receptor of MusC.
靶标/特异性:
Detects mouse and rat Nampt. Does not cross-react with human Nampt, mouse adiponectin, mouse resistin, mouse vaspin or mouse RBP4.
保存温度:
+4°C
运输温度:
BI
产地:
瑞士
灵敏度:
50pg/ml
检测范围:
0.5 to 32ng/ml
检测方法:
Colorimetric
样本类型:
Serum
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