Peroxiredoxin 4 Antibody / PRDX4-单抗-深圳欣博盛生物科技有限公司

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Peroxiredoxin 4 Antibody / PRDX4

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5648SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

Peroxiredoxin 4 Antibody / PRDX4

产品描述:

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX IV gene is expressed in many tissues. It exists as a precursor protein, which is only detected in testis, and aprocessed secreted form. PRX IV is highly expressed in lung cancer and is necessary for the promotion of lung cancer in vitro. Studies have demonstrated that PRX IV positive expression is significantly correlated with recurrences and shorter disease-free survival in patients with early-stage lung squamous cell carcinoma, and therefore can be used as a prognostic marker in lung squamous cell carcinoma.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA

同种型:

Mouse IgG2a, kappa

免疫原:

A recombinant full-length human PRDX4 protein was used as the immunogen for the Peroxiredoxin 4 antibody.

克隆性:

Monoclonal (mouse origin)