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折扣/货期| 货号：AG-CR1-3636-M001 | 规格：1 mg | 目录价：￥540 |
| 货号：AG-CR1-3636-M005 | 规格：5 mg | 目录价：￥1200 |
| 货号：AG-CR1-3636-M025 | 规格：25 mg | 目录价：￥4800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-2545920
别名:
2-(4-(1-Methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)-phenoxymethyl)quinoline; MP-10
产品描述:
Potent and selective phosphodiesterase 10A (PDE10A) inhibitor (IC50=1.26nM) in vitro and in vivo. PDE10A is a cGMP and cAMP degrading PDE isozyme with neurological importance and was shown to be implicated in the regulation of energy homeostasis. Inhibition of PDE10A leads to interference of the breakdown of the secondary messenger cAMP and cGMP. Anti-psychotic agent. Useful for the treatment of schizophrenia. Anticancer agent. Inhibits colon tumor cell growth for which high levels of PDE10A have been reported. Antiobesity and antidiabetic agent. Induces browning in white adipose tissue (WAT).
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
392.5
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
898562-94-2
分子式:
C25H20N4O
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