BMS-309403-抑制剂-深圳欣博盛生物科技有限公司

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BMS-309403

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3640-M001	规格：1 mg	目录价：￥420
货号：AG-CR1-3640-M005	规格：5 mg	目录价：￥840
货号：AG-CR1-3640-M025	规格：25 mg	目录价：￥2640

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BMS-309403

别名:

BMS309403; BMS 309403; FABP4 Inhibitor; 2-[[2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]acetic acid

产品描述:

Cell permeable, potent and selective fatty acid binding protein 4 (FABP4; A-FABP; ALBP; adipocyteP2 protein) inhibitor that competitively targets the fatty acid-binding pocket (Ki= <2nM). Inhibits FABP3 (muscle) and FABP5 (epidermal) with lower affinity (Ki=250nM and 350nM, respectively). FABP4 is an intracellular lipid-binding protein responsible for the transportation of fatty acids. It is expressed primarily in adipose tissue and is associated with inflammation, obesity, diabetes and cardiovascular diseases. Glucose uptake stimulator. Reduces blood glucose levels and increases insulin sensitivity in a mouse model of obesity. Protects against the development of insulin resistance associated with genetic or diet-induced obesity in mice. Anti-atherosclerotic. Decreases fatty acid uptake in adipocytes in vitro and reduces atherosclerotic lesion area in a mouse model of atherosclerosis.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

474.6

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)