官网链接
折扣/货期| 货号：AG-CR1-3640-M001 | 规格：1 mg | 目录价：￥420 |
| 货号：AG-CR1-3640-M005 | 规格：5 mg | 目录价：￥840 |
| 货号：AG-CR1-3640-M025 | 规格：25 mg | 目录价：￥2640 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BMS-309403
别名:
BMS309403; BMS 309403; FABP4 Inhibitor; 2-[[2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]acetic acid
产品描述:
Cell permeable, potent and selective fatty acid binding protein 4 (FABP4; A-FABP; ALBP; adipocyteP2 protein) inhibitor that competitively targets the fatty acid-binding pocket (Ki= <2nM). Inhibits FABP3 (muscle) and FABP5 (epidermal) with lower affinity (Ki=250nM and 350nM, respectively). FABP4 is an intracellular lipid-binding protein responsible for the transportation of fatty acids. It is expressed primarily in adipose tissue and is associated with inflammation, obesity, diabetes and cardiovascular diseases. Glucose uptake stimulator. Reduces blood glucose levels and increases insulin sensitivity in a mouse model of obesity. Protects against the development of insulin resistance associated with genetic or diet-induced obesity in mice. Anti-atherosclerotic. Decreases fatty acid uptake in adipocytes in vitro and reduces atherosclerotic lesion area in a mouse model of atherosclerosis.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
474.6
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
300657-03-8
分子式:
C31H26N2O3
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询