Piccolo Antibody-单抗-深圳欣博盛生物科技有限公司

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Piccolo Antibody

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-188D

规格：100 µg

目录价：￥4145.4

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Piccolo Antibody

别名:

ACZ Antibody, Aczonin Antibody, PCLO Antibody, Pico Antibody, presynaptic cytomatrix protein Antibody

产品描述:

Mouse Anti-Human Piccolo Monoclonal IgG2b Kappa

反应种属:

Human | Mouse | Rat

宿主来源:

Mouse

实验应用:

WB | ICC/IF | ELISA

靶标/特异性:

Detects ~550kDa. No cross-reactivity to Bassoon.

同种型:

IgG2b Kappa

推荐稀释度:

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Human full length recombinant protein (GenBank ID: BC001304.1)

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

6H9-B6

纯化方式:

Protein G Purified

偶联:

Unconjugated

产品浓度:

1 mg/ml

保存温度:

-20ºC

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).

Accession #:

NP_001104266.1