PILRA Antibody-多抗-深圳欣博盛生物科技有限公司

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PILRA Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：30-252

规格：100 ul

目录价：￥9108.45

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PILRA Antibody

别名:

PILRA, FDF03

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA,WB

克隆性:

Polyclonal

纯化方式:

Antibody is purified by peptide affinity chromatography method.

偶联:

Unconjugated

产品浓度:

batch dependent

保存温度:

For short periods of storage (days) store at 4˚C. For longer periods of storage, store PILRA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

产地:

美国

生产商:

Prosci

功能与背景:

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.

Accession #:

NP_840057

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