深圳欣博盛生物科技有限公司 a1

货号:GTX130433 规格:100μl 目录价:¥4000
货号:GTX130433-S 规格:25μl 目录价:¥1700
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PKC alpha (phospho Thr497) antibody
别名:
protein kinase C alpha , AAG6 , PKC-alpha , PKCA , PKCI+/- , PKCalpha , PRKACA
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody is raised against human PKC alpha phosphorylated at Thr497. Based on sequence homology, it may cross react with human PKC beta1, beta2, gamma, delta, epsilon, zeta, eta, and theta.
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Thr497 of human PKC alpha. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.44 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
77
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq]
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