PMS2 antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

PMS2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX30731

规格：50μg

目录价：￥4700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PMS2 antibody

别名:

HNPCC4 , MLH4 , PMS1 homolog 2, mismatch repair system component , PMS2 , PMS2CL , PMSL2

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

IHC, WB

同种型:

IgG

免疫原:

Synthetic peptide surrounding amino acid 846 of human PMS2

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

95.8

产品形式:

Liquid

存储溶液:

PBS, 0.5% BSA, 30% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC; also known as Lynch syndrome) and Turcot syndrome. [provided by RefSeq, Apr 2016]

您可能感兴趣的产品

Biotinylated Anti-Human SCGF-beta

货号：500-P99GBT-25UG

Biotinylated Anti-Human Fractalkine (CX3CL1)

货号：500-P98BT-25UG

Biotinylated Anti-Human TARC (CCL17)