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折扣/货期| 货号：22053-1 mg | 规格：1 mg | 目录价：￥563 |
| 货号：22053-10 mg | 规格：10 mg | 目录价：￥4409 |
| 货号：22053-25 mg | 规格：25 mg | 目录价：￥8643 |
| 货号：22053-5 mg | 规格：5 mg | 目录价：￥2546 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ponesimod
产品描述:
A potent S1P1 receptor agonist (IC50s = 6, >10,000, 2,068, 1,956, and 142 nM for S1P1-S1P5, respectively, in a radioligand binding assay); selectively activates S1P1 in a GTPγS assay (EC50s = 5.7, >10,000, 105, 1,108, 59.1 nM, for S1P1-S1P5, respectively); reduces the number of circulating lymphocytes in rats in a dose-dependent manner; reduces edema, protein extravasation, neutrophil activity, and skin levels of the proinflammatory cytokines IL-1β, IL-6, IFN-γ, and TNF-α in a mouse model of delayed-type hypersensitivity; prevents footpad swelling in a rat model of adjuvant-induced arthritis
保存温度:
-20
运输温度:
-20
预期分子量:
461
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
854107-55-4
分子式:
C23H25ClN2O4S
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