深圳欣博盛生物科技有限公司 a1

Siponimod
货号:22057-1 mg 规格:1 mg 目录价:¥482
货号:22057-10 mg 规格:10 mg 目录价:¥3390
货号:22057-25 mg 规格:25 mg 目录价:¥6727
货号:22057-5 mg 规格:5 mg 目录价:¥1943
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Siponimod
别名:
BAF312
产品描述:
An S1P1 and S1P5 receptor agonist; selective for S1P1 and S1P5 over S1P2, S1P3, and S1P4 (EC50s = 0.39, 0.98, >10,000, >1,000, and 750 nM, respectively, in GTP-γS binding assays); reduces lysophosphatidylcholine- or psychosine-induced demyelination in mouse organotypic cerebellar slice cultures at 10 nM; decreases plasma levels of urea and creatinine in a rat model of renal ischemia-reperfusion injury at 10 and 30 mg/kg; reduces disease severity in a rat model of EAE at 0.3 and 3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
516.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1230487-00-9
分子式:
C29H35F3N2O3
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