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折扣/货期| 货号：AG-40B-0123-3010 | 规格：3 x 10 ug | 目录价：￥3600 |
| 货号：AG-40B-0123-C010 | 规格：10 ug | 目录价：￥1800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
POP1 (human) (rec.) MultiPack
别名:
Pyrin Domain-containing Protein 1; PAAD-only Protein 1; Pyrin-only Protein 1; PYC1
产品描述:
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family (NLRs), including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). Pyrin domain-containing protein 1 (POP1) interacts with the protein Asc (Pycard) and modulates the interaction of Asc to NLR proteins.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~38 kDa
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
促销活动
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