PRDX3 Antibody / Peroxiredoxin 3-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

PRDX3 Antibody / Peroxiredoxin 3

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31762

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PRDX3 Antibody / Peroxiredoxin 3

产品描述:

Peroxiredoxin 3, also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human protein shares 86% amino acid sequence similarity with mouse, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of Peroxiredoxin 3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that Peroxiredoxin 3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P, ICC, IF, FACS

同种型:

Rabbit IgG

免疫原:

Human partial recombinant protein (AA 110-256) was used as the immunogen for this PRDX3 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the PRDX3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

您可能感兴趣的产品