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折扣/货期| 货号：SIH-626-5MG | 规格：5 mg | 目录价：￥1915.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Pridopidine
别名:
4-(3-(Methylsulfonyl)phenyl)-1-propylpiperidine; ACR16
产品描述:
Neuroprotective
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
281.4
产品形式:
White powder
产地:
加拿大
功能与背景:
Potential treatment for Huntington’s disease, Parkinson’s disease, and schizophrenia (1,2). Able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics (“dopamine stabilizer”) (3). More recent studies have attributed pridopidine’s effects to its being a more potent sigma-1 ligand than a D2 ligand (4,5). Displays neuroprotective/restorative effects (6,7) and ameliorates central features of amyotrophic lateral sclerosis pathology (8) in a sigma-1-mediated manner.
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
346688-38-8
分子式:
C15H23NO2S
溶解度:
May be dissolved in DMSO (10 mg/ml)
PubChem CID:
9795739
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