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折扣/货期| 货号：AG-40B-0121-3010 | 规格：3 x 10 ug | 目录价：￥5040 |
| 货号：AG-40B-0121-C010 | 规格：10 ug | 目录价：￥2520 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Profilin (Toxoplasma gondii) (rec.)
别名:
Inflammatory Profilin
产品描述:
TLR11, an innate sensor for profilin (Toxoplasma gondii), is an intracellular receptor that resides in the endoplasmic reticulum. The 12 membrane-spanning endoplasmic reticulum-resident protein UNC93B1 interacts directly with TLR11 and regulates the activation of dendritic cells in response to profilin (Toxoplasma gondii) and parasitic infection in vivo. TLR12, a previously uncharacterized TLR, also recognizes profilin from Toxoplasma gondii. TLR12 is sufficient for recognition of profilin by plasmacytoid dendritic cells (pDCs), whereas TLR11 and TLR12 are both required in macrophages and conventional DCs. In contrast to TLR11, TLR12-deficient mice succumb rapidly to T. gondii infection.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~20kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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