Progranulin (human) ELISA Kit-人ELISA试剂盒-深圳欣博盛生物科技有限公司

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Progranulin (human) ELISA Kit

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-45A-0018YEK-KI01	规格：96 wells	目录价：￥7320
货号：AG-45A-0018YTP-KI01	规格：2 x 96 wells	目录价：￥13200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Progranulin (human) ELISA Kit

别名:

Proepithelin; PEPI; PC Cell-derived Growth Factor

产品描述:

Progranulin (PGRN) is a widely expressed pluripotent growth factor that plays a role in processes such as development, wound repair, and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD but also for other types of Alzheimer‘s disease (AD). This new data even suppose the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory diseases like arthritis. Progranulin expression in plasma predicts GRN mutations status, independently of symptom onset proximity. Progranulin loss-of-function mutations are among the most frequent genetic causes, responsible for 20% of familial FTLD. If a patient carries a mutation in the progranulin gene, it can be detected using AdipoGen's Progranulin (human) ELISA Kit. This is the only and unique kit on the market detecting all mutations of Progranulin [Reference 58].

靶标/特异性:

Detects human progranulin.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

32pg/ml

检测范围:

0.063 to 4ng/ml

检测方法: